Final October, I entered the lab of Kingdom Supercultures in Brooklyn, New York, the place unlabeled jugs of almond milk had been strewn throughout the breakroom desk. House owners Ravi Sheth and Kendall Dabaghi had been taste-testing milk diversifications utilizing microbe cultures initially present in fermented meals comparable to kimchi, sauerkraut, vinegar and the like. They had been looking for the proper mixture that might change the substitute emulsifiers and gums sometimes used to create a silky and easy beverage.
Industrialized meals are affected by components and substances—stabilizers, synthetic preservatives, sweeteners and dyes—meant to have an effect on various traits from texture to taste and a lot extra. Meals labels for plant-based merchandise and different processed meals are sometimes so prolonged, it begs the query: Is that this even meals anymore?
In an effort to interchange chemical components with extra pure alternate options, corporations comparable to Kingdom Supercultures are drawing on ancestral wisdoms and substances. The Stay Inexperienced Co., primarily based in Boston, makes use of a know-how platform it calls Charaka to create plant-derived substances that may operate throughout varied molecular and bioactive compounds—whether or not the main focus be chemical, mechanical, practical, dietary or sustainable. The hope is to transition from “plant-based” to “plant-only” meals. In the meantime, Argentina-born Michroma makes use of fungi to create pure meals colours.
Processed meals as we all know them right now date again to the late 18th and early nineteenth centuries, when meals was manipulated, largely, to cater to the rising navy. Then got here pasteurization and canning within the late nineteenth century, and later, ready-to-eat meals that roared onto suburban grocery store cabinets. Throughout this time, ingredient corporations tinkered with chemical isolates to create mechanisms that made meals extra secure, handy and accessible.
“Within the Sixties, meals security regulators within the US, Europe and different areas of the world, accepted meals components to guarantee shoppers that their use in foodstuff was protected,” says licensed meals scientist Kantha Shelke. The FDA now maintains a database of greater than 3,000 added substances used by shoppers and the meals trade. The record contains all the pieces from high-fructose corn syrup and guar gum to nitrates and nitrites to synthetic dyes and hormones.
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As components and substances have skyrocketed, well being considerations are additionally on the rise. In accordance with a research by the American Academy of Pediatrics, concern concerning meals components has elevated previously 20 years, notably amongst youngsters whose creating our bodies are extra vulnerable to affect. It additional explains that some synthetic meals colours could also be related to the exacerbation of ADHD; nitrates and nitrites might intervene with thyroid hormone manufacturing, whereas different components and substances can contribute to oxidative stress.
“Within the final 20 years, meals components proliferated in meals manufacturing as a result of rising demand for clear label meals and practical meals with scientifically sustained bioactivity and claims,” Shelke says, including that the trade funding in “cleaner” alternate options lacks unfavorable notion and is seen as extra sustainable. Some argue that FDA rules and present necessities for a “typically acknowledged as protected” (GRAS) designation are merely inadequate. Conversely, the European Union has banned sure components that the FDA nonetheless permits. That features the not too long ago banned titanium dioxide—present in vibrant candies, soups, sauces and extra—which the European Meals Security Authority states is unsafe for consumption. This ingredient is, nonetheless, nonetheless being utilized in American merchandise.
Utilizing microorganisms, comparable to those who Kingdom Supercultures is working to develop, to supply meals components requires much less water and power than byproduct reuse. This might doubtlessly eradicate the intensive and costly use of farmland for crops comparable to corn for high-fructose corn syrup and soybeans for hydrogenated oils.

Ravi Sheth and Kendall Dabaghi, founders of Kingdom Supercultures.
When Kingdom Supercultures launched in 2020, Dabaghi and Sheth needed to construct their very own atlas of pure microbial-based substances that mimic the efficiency of business components. “As a substitute of getting a library of synthetic chemical substances, we need to begin with a library of those pure microbial strains,” says Dabaghi, who co-founded the corporate after researching microbiome and machine studying at Columbia College.
Scientists at Kingdom Supercultures use machine studying and different applied sciences to discover hundreds of thousands of undiscovered, uncharacterized microbes that stay inside fermented meals. They then extract microbial strains, merge them with different isolates and design what they name “supercultures.”
“We expect we are able to compound them collectively in several proportions and combos and equally have an effect on taste, texture and practical properties—however in a way more wholesome and sustainable manner,” says Dabaghi. To this point, they’ve crafted these components for plant-based cheese, yogurt, kombucha and not too long ago a vegan butter completely for famed Eleven Madison Park in Manhattan. Their supercultures are additionally getting used for private care merchandise and can ultimately broaden to non-vegan meals.
Because the plant-based sector continues to develop, these microbial farming corporations may allow shopper packaged items (CPG) corporations to have the ability to tune the sensory and practical properties of their merchandise with plant- and food-derived substances. However will these extra “pure” components be any higher than their “processed” counterparts? Whereas the analysis taking place within the biotech area appears promising, there’s nonetheless quite a bit that has but to be studied.
“Customers, regardless of missing the basics of meals science and diet, are directing the trade towards bioactive and technologically related compounds that may do no hurt,” says Shelke, who believes time and rigorous analysis will inform whether or not or not the human physiology will adapt to the ever-evolving meals area and the foodstuffs being produced. “Paradoxically, there’s plenty of science, know-how and manipulation to make meals seem as if made by nature and minimally processed.”
Whereas the way forward for components and substances is now being written (or coded), the avenue to cleaner ingredient labels and a extra simply meals system is ripe with potential.